I did an interior story of a main work and named the chapters to further the differentiation. Some liked it while others didn't because they felt the technique gave up part of what they were about to read, which was certainly a justifiable contention.
I've thought about this a great deal, and I think it relates as much to genre and voice as anything else. You might want to consider:
A children's story could be ideally suited for a chapter title (voice cetainly would allow it), where a thriller, such as I write, might not. As I say, I've only done this once and the verdict is still out on whether I'm going to ultimately retain the chapter titles in the interior element. For me, it's a very interesting subject.