Sometimes, if you nail down a particular human behavior pattern, you'll get dozens of people thinking you were writing about them. I regard that as a personal triumph.
In general, people will always see themselves in your writing when they aren't there, and will fail to see themselves when they are.
Stuff you can do:
1. Say no, you didn't; but would they like to be written in next time?
2. Tell them there are all sorts of non-matching facts about that character which didn't appear in the book, but which may get mentioned next time.
3. Say "No, not quite," then launch into a very long, detailed discussion of your book. If you sufficiently overtax their attention span, they may never ask again.
4. Always check to make sure there isn't a real left-handed Seventh Day Adventist endodontist named Altoona G. Clarke before you write one into your book. If you find twelve of them, you're also in the clear.
5. Grin and bear it. You can't control the ways people read your books.