I went to the KYRW workshop in March. The two major guests were an author that made the jump from epublishing and a co-founder of Resplendence E-Publishing. Between the two of them the workshop was very enlightening.
The author wrote more specualtive fiction. So, the jump was easier than if she wrote romance. However, she did say that because of her genre and the fact that she had a fan base from e-publishing she felt that when she went in search of agent the process was easier than expected.
The representative from the e-pub stated that their biggest selling genre was male on male erotic. For all tense in purposes she said if some one had a well written male on male they would be published, period. Their markets after the big ONE went as follows: orgie-erotica, hedero-erotica, historical romance, and finally paranormal romance made up the big five.
I suppose it depends on what you write and how you write. I have often wondered about using e-publishing as a stepping stone or sticking with it for the long hall. For as much as I would love to say e-pub is for me because its better for the environment I think I may be more of a book snob(I love the smell of a book) and cannot lock the thought down. To each their own, I suppose.