Shawn, did you actually get a hit in those last five queries?
I have gleaned some more agents to query, about a dozen or so. So I guess I'll continue to try. I am concerned that the most consistent response is "just not enthusiastic/excited enough about the plot/story/characters/premise." I have had a couple agents tell me that I have good writing skills and I've succeeded with characterization, world-building, etc., so there is apparently some promise to the novel. And I've had several nibbles and three requests for the complete manuscript.
I've thought seriously about workshopping it again or sending it to a couple workshop writers to get an opinion about why it isn't, quite, flying. I hate to spend all my time on this one, though, rather than working on a new book.
Maestro, is that 200 agents in the fantasy genre? Many don't take fantasy. A lot aren't accepting new clients right now.
The query letter has been workshopped. I'm pleased with it. And in a way, it got me my day job. When I interviewed for this job, the interviewer wanted to see what I did with creative writing. So I sent her this query letter and the one-page prologue to a mystery I'm developing. I got the job (which I'd better get back to if I want to keep it!).