I'm not a huge fan of the multi-POV epistolary form that had it's heyday back in the turn of the 20th century. That said, I think Stoker's was the only one I ever managed to get all the way through.

I don't know that it would work in a contemporary setting, since so much of our media has left the medium of being written. Newspaper articles could be used, but the personal narrative would be tough since most people don't journal any longer. I suppose you could include tweets for the personal narrative, but would be hard to pull of something coherent.

As far as characters I always like Van Helsing, admittedly, some of that may come from him being portrayed by Sir Anthony Hopkins in the film. I also saw the Coppola film first and then read the book.