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Biology: AI Solves Puzzle of How Proteins Fold in 3D

Alessandra Kelley

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https://www.bbc.com/news/science-environment-55133972

A London-based AI laboratory has succeeded in predicting the real-world three-dimensional shapes of proteins it's presented with with a high degree of accuracy. This is excellent news for biological and medical research.

One of biology's biggest mysteries has been solved using artificial intelligence, experts have announced.

Predicting how a protein folds into a unique three-dimensional shape has puzzled scientists for half a century.

London-based AI lab, DeepMind, has largely cracked the problem, say the organisers of a scientific challenge.

Prof Andrew Martin from University College London (UCL), a former Casp entrant and assessor, told BBC News: "Understanding how a protein sequence folds up into three dimensions is really one of the fundamental questions of biology.

"The whole way in which a protein functions is dependent on its three-dimensional structure and protein function is relevant to everything in health and disease.

"By knowing the three-dimensional structures of proteins we can help to design drugs and intervene with health problems whether those be infections or inherited disease."