If you just want some few readers who like your quirky, between-genre books, self-publishing at least gets those books out to some readers. It's probably the only way to get them out to any readers at all unless you hit the trade-publishing lottery.
But the truth about what readers want is the same for trade publishing and self-. Books that are in popular genres, smack dab in the middle of them, tropey as can be, are the ones that sell well. ("Well," by which I mean 10,000 copies and better.) To learn more, study the best seller lists at Amazon (it would be similar at other vendors, but Amazon US is the easiest to use). Here's all ebooks:
https://www.amazon.com/Best-Sellers-Kindle-Store-eBooks/zgbs/digital-text/154606011 They are, you notice if you dig down into product descriptions and reviews, smack dab in the middle of political thrillers, of contemporary romance, of vampire romance, of epic fantasy, of police procedurals. Today, nine of the top 10 are self-published. Some days only 6 or 7 of the top 10 are self-published. One in the top 50 novels might be a literary book of some sort, this year's darling from the Big Five, but 49 are genre books.
Therefore, publishers also aren't snapping up literary and between-genre books either, for the ones who haven't gone broke understand the marketplace. A good thriller or cop book with series potential, a romance that involves a big family so a series can be spun out of it: that's where the money is. While people can self-publish for fun, or without hope of many sales, the ones who do well are publishers and know it; they think like publishers and they have business plans like publishers and they do audience analysis like publishers.
No, likely 90% of readers don't care how well or (within reason) how poorly they are written (or else many trade-published books I could name wouldn't have been best-sellers either). More than 90% can't tell the difference between trade and self-published books (at least the ones that have good covers), and if they could tell, they wouldn't care--though they like the much-lower prices a self-publisher is able to offer.
The reality about lack of caring about style and deftness of language and technique disappointed me at first, but then I realized I still want to edit for language for as long as I can justify doing so. Still, I'm aware that it's a time sink that is only compensated by the 1 out of 25 reviews that note it, which strangely enough my bank does not take in lieu of a mortgage payment. (If a book less per year means $5000 less income per year, then it's quite the self-indulgence, wouldn't you agree?) In short, fine language is a thing that English professors and agents care about but not the vast majority of readers. If the fine language comes in descriptions that drag down the pace of a book, they downright hate it.
Another thing that surprised/disappointed me is that most readers will not follow authors across genres. I certainly do. Once I find a style I like, I'll read everything that author writes and seek out the pen names. But no, not most readers. Eventually the light bulb went off for me: I was thinking like a trained writer, not a typical reader. Most readers aren't writers (or English profs) and they don't think like them. I've learned to think like a publisher, for that is what I am (every day, after I'm done being the writer), and that requires understanding the non-writing reader and what she wants and will click on and pay her credit card bill to own.
Most readers want a good, fast-paced tale with likable characters. They either get recommendations from friends or search a particular sub-genre for new titles and authors. Most readers don't know and don't care who published it. That's the reality of the business of selling books in 2018.
Good luck, whatever you decide to do!