He's worked since he got married, but I think he's been more behind-the-scenes since they had the kids.
Regardless, the question was about people whose careers aren't what they used to be, who still have the clout to secure financing, but could use a revival in a good series. That's for sure not Clooney. Likewise a bunch of the kid actors I don't think ever had much clout. Like, could Mekhi Pfiffer ever get financing on his name alone attaching to something?
Clooney can pick up the phone and secure enough to start a superhero franchise of his own, I'm pretty sure, even with a bunch of lost money trailing behind him. He's Clooney. Likewise Jackman, who has a lot more good money recently under his name, can, I'd wager, get whomever and whatever he wants with a phone call.
Can Cusack? He does still get work, and has decades of friends and good will and good work, and I'd think he can call up money and pals (god knows he's given out enough work to get some back) if he wanted, but he's not the hot property he was, and some critically-hailed cable or streaming thing starring him could put him back up there. That was the way I was thinking about the question anyway.
Though the Cusacks seem to swap a bit and I feel like she's been more up recently, heh. I <3 them both, especially together (GPB is the epitome, imo, even tho it wasn't portraying the actual relationship like SA). Someone put them in something together.