There's no one answer to this question, I'm afraid.

Every book is different, so every book will get a different response.

Some books have no chance of getting a response at query stage because they're so poorly written no agents will know what to say. Some books have such a good chance of being published that they'll get responses from almost every agent queried.

If you want to understand how this works, look up Slushkiller, on Making Light.