I apologize if this question offends you guys here, but can a character's sexual orientation be so outlandish they can't be taken seriously anymore, regardless of the setting? Just for example, in this futuristic (not quite cyberpunk, it's set in 2021 Indonesia) detective story i'm writing, the main character is a pansexual trans female crossdresser, while the villain is a lesbian non-binary incest-rights activist who has heterochromia.