Similar to the files in the above post, I use OneNotes which can be found in the Office 2007 package.
It's just like having a notebook full of papers and oodles of tabs. For me, this is perfect, since I move from country to country & really don't have a sense of humor when it comes to lugging all my notebooks (I won't allow them to be packed/shipped only to be lost) instead of a change of clothes.
AND it's simple-stupid...which...since I'm blonde...need I really say more?