Jonathan - I guess that would depend at what point in the story we are in with the MC. For most of it, he would want to ask anyone who knew or God himself, if he exists, not that Jonathan can believe it. In his opinion, something like God is too fantastical an idea to be real, life is too boring and mundane for that. Anyhow, if he could, he'd ask God "So, if all life for most people is just this repeated rat race to get by, pay bills, and work themselves into a boring death. What's the point?"
If your MC could pick one super power (that they don't already have, if they do have powers), what would it be and why?