I believe my "How to Flirt With Girls" guidelines work just as well for having a meaningful conversation with women. So:
1. Eye contact is key. Oh, I don't mean eye contact with her EYES--your gaze should never stray from her chest. Women love this, trust me.
2. Answer every question she asks with a leer and a sexual innuendo. Example: "Would you STOP staring at my chest?" *leer* "What would you prefer I stare at?" Bonus points if you waggle your eyebrows at her while asking this.
3. In the middle of a conversation with her (especially if she is telling you some really deep, private and personal information), belch loudly, scratch your belly (remember, guys - no butt scratching in front of her until the SECOND date), and ask her to grab you another beer.