Who Publishes Science Based Fiction?

I think that sometimes, that kind of book can even bridge into Fiction/Lit. Think of Jurassic Park--a hypothetical near-future based on real science (unlikely science, but real science). It's shelved in Fiction, not sci-fi. Can't come up with another example off the top of my head, but I know there's more. But that kind of just-a-few-steps-forward sci-fi book can be marketed for either genre, so it'd be worth checking out publishers for both.

Ben Bova's publisher, Greg Bear's publisher, Kim Stanley Robinson's publisher, Isaac Asimov's publisher(s), and so on and so forth.

And this is moving into the SF parent forum--since it is about fiction, and not fact.

Hope you understand

Most SF publishers would probably take a look at it. Robert J. Sawyer has a few books that aren't very futuristic or "science fictiony" (though they are probably more so than what you seem to be planning). Greg Bear is a good writer of fiction based on real science in the present or near future. There's a lot of "what if" books out there that don't involve distant future civilizations, space ships, death rays, or time travel.

You should see who published the novels listed at LabLit:
http://www.lablit.com/the_list

There focus on fiction that includes "realistic scientists as central characters and portrays fairly realistic scientific practice or concepts, typically taking place in a realistic – as opposed to speculative or future – world."

If you call it a 'techno-thriller' then most publishers of thrillers/commercial fiction would be possibles.