... take Twilight. It's author:
From the 'Getting Published' section of the page.
http://www.stepheniemeyer.com/twilight.html
... sent out around fifteen queries (and I still get residual butterflies in my stomach when I drive by the mailbox I sent the letters from—mailing them was terrifying.). I will state, for the record, that my queries truly sucked, and I don't blame anyone who sent me a rejection (I did get seven or eight of those. I still have them all, too). The only rejection that really hurt was from a small agent who actually read the first chapter before she dropped the axe on me.
From the 'Getting Published' section of the page.
http://www.stepheniemeyer.com/twilight.html