Sage, I agree, you should absolutely query her. Agents know it can take a while to write a new manuscript. I don't think she would mind that two years have passed at all!
So, Joan had partials from me on two different manuscripts (explanation for that a few posts up) and wrote this morning to say she'd read the pages on the first one and LOVED them (caps hers!). She asked me to send the fulls of both manuscripts. When she confirmed, she said she was "really eager to read" - maybe she says that to all the girls, but I'm choosing to feel giddy about it.