A synopsis is the whole plot of your book, whether that be summarized to one page (a difficult task, but you should do it) or a 10-page overview (which almost no one wants, these days; you're more likely to be asked for one page).
The one-page synopsis can be single-spaced. Every other length of synopsis should be double-spaced (one blank line between each typed line, like in your manuscript). Never use less than 10pt font, and even then, you're reeeeally pushing it. The default is 12pt.
I find the best way to write a synopsis is to first go through the book and locate the "turning point" of each scene, i.e. the moment where things irrevocably change, whether that be due to someone's revelation, someone's action, an event occurring, etc. Your synopsis will consist of stringing all these turning points together and then smoothing the transitions so it makes coherent sense when read. If you need to make it shorter, you cut out the turning points for the subplots and summarize/gloss over things that are less important.