Thank you RLGreenleaf! To add to the confusion I sent out another huge batch of queries today, and got a reply late afternoon from A Big Literary Agent (who I only had the gall to query because I had got to that punch drunk stage where what you are doing ceases to feel real) who once again loved my book, said it "deserves to find a good home", but that he didn't personally feel sufficiently "fired up" about my characters. No mention of problematic prologue (good) but everyone has raved about my characters before, and I thought it was the one indisputable solid good thing in the book! Still, positive personal reply from A Big Agent, so I'm taking that as a win. In fact, if I don't find representation it might well be the high watermark of my publishing career