Awww, thanks everyone! This is my first book and it is nice to be able to hear from people going through the same trials as I don't know any other fiction writers.
I got another rejection today, but this time there was some specific feedback. It was flattering despite the aspects they thought were not a good fit for them. I am not sure I agree with all the feedback, as it is very subjective, but I think it's a good sign that someone thought well enough of the manuscript to provide specific feedback even if they didn't think it was right for their house. They sort of implied that they were willing to look at it in the future again, but I think too many changes to the core of my story/characters would be required to be in line with the type of romance they want the book to become. This specific publisher does require happy endings (or happy for now), but when I submitted the ms, they asked me about this and I told them at best the ending could be interpreted as "happy for now" and sent them the last few paragraphs to make sure it was worth their time. They still took a stab at reading the whole thing. So I guess that's good that they still wanted to give it a go after reading the less than happy ending.
Today's rejection didn't hurt as much as the first, I think because the form letter was kind of a dagger, it felt much colder than the personalized rejection I got today.
I have another requested full out, which is making me really nervous. This publisher does not require happy endings, so I am going a little nutz-o waiting on a response!