Queried Ms. Brady a few days back and got a very nice personalized rejection, and queried Ms, Volpe today (wasn't sure if their policy was don't query more than one agent at once, or don't query more than one at all). Here's hoping.
My impression is that a "no" from one agent is a "no" from all agents; therefore, you aren't supposed to query another agent with the same query letter. However, if you heavily revise your query letter (and preferably your MS too), you can resend it (even to the same agent.)
EDIT: Yup. From their submissions page:
Do not query more than one agent at New Leaf Literary & Media, Inc.
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