So would it be acceptable to stress the importance of the words under these certain circumstances?

Here are the examples I want to use italics to stress the words.

1
He used the medicine to alleviate his anxiety in social situation. looking at his classmates that had tormented him for so long, those old memories of their torments began to activate his anxieties. His hands began shaking almost violently. He needed that medicine, and he needed it right now.

Is that acceptable?

2

Gregory was editing the new book by his friend, The Rearguard.


Number two is a fake title. Is it acceptable to use italics on the title of the book?