I've just had an R&R from Entangled. The editor replied to my submission by saying she enjoyed the MS but would need to see changes made before she could consider going further with it and asked if I would be interested. I was, so she then replied with a list of things that weren't working for her. She told me I could resubmit at any time and to contact her if I had any questions in the meantime.

If you look on Query Tracker, it seems like the six month window is a common thing with Entangled, but perhaps slightly different to an R&R. If you're happy to make the changes suggested, then I'd go for it - I'd almost guarantee it will make your manuscript stronger, which will also help when you're submitting elsewhere so it seems like a win/win situation.

Good luck! (And if you're wondering, my R&R ended up as a rejection).