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Again, this relates mostly to non-fiction, but at a recent BAIPA meeting (Bay Area Independent Publishers Association) Alan Rinzler, head of Jossey-Bass, said that he thought about 5% of self-published books were being acquired by traditional houses. (BTW I assume he meant "properly self-published" books, i.e. edited, designed, produced professionally.).
I don't know what the acceptance rates are for non-fiction at commercial houses, but for fiction (about which the OP was inquiring), it's about 2-3% of manuscripts submitted. For the sake of ease, let's split the difference and say 2.5%. Then consider that 90% of what's submitted is completely unpublishable dross, and another 5% is good but either not quite good enough or not right for the targeted publisher.
Of the remaining 5%, half of it gets accepted. That's 50% of the work that's well-written, well-edited, and properly targeted (which I'd equate to '"properly self-published" books, i.e. edited, designed, produced professionally').
So if Mr Rinzler's numbers are correct, this shows that, if you want a commercial contract, you still have a substantially better chance (50% vs 5%) of getting one by submitting well-written, well-edited, properly targeted fiction to commercial publishers, not self-publishing it, even properly.
For those who aren't interested in commercial contracts, this is, of course, meaningless.